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First published in 1986 under the editorial direction of Dr. Henry J.M. Barnett, this encyclopedic, yet readable text has served as a "one-stop shop" for generations of practitioners seeking authoritative coverage of the scientific and clinical aspects of stroke. The 4th Edition features a new editorial team led by former co-editor Dr. J.P. Mohr, offering updated and expanded coverage of epidemiology and prevention, clinical manifestations, diagnosis, specific medical diseases related to stroke, pathophysiology, and medical and surgical therapy. Explains the mechanisms of stroke and stroke-related diseases. Provides comprehensive clinical guidance-from recognizing the clinical manifestations of stroke and using the latest laboratory and imaging studies to arrive at a diagnosis to medical and surgical treatment planning. Features a new editorial team led by former co-editor Dr. J.P. Mohr. Devotes a new section to Epidemiology and Prevention, with chapters on distribution, risk factors and prevention, and outcomes. Offers fresh perspectives from new authors on the latest advances in imaging, addressing functional neuroimaging, fast MRI, and more. Includes an expanded Pathophysiology section, with new chapters on excitotoxicity, apoptosis, inflammation, intracellular signaling, recovery of function, and more. Contains a reorganized and expanded Therapy section, with separate subsections on medical therapies (including new anticoagulants and neuroprotection agents) and surgical therapies (including new procedures for prevention and repair of stroke damage). With over 130 additional contributors.… (more)
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1. Distribution of Stroke -- 2. Risk Factors for Stroke and Stroke Prevention -- 3. Outcome Following Stroke -- 4. Classification of Ischemic Stroke -- 5. Internal Carotid Artery Disease -- 6. Anterior Cerebral Artery Disease -- 7. Middle Cerebral Artery Disease -- 8. Posterior Cerebral Artery Infarcts -- 9. Anterior Choroidal Artery Infarcts -- 10. Vertebrobasilar Infarction -- 11. Lacunes -- 12. Cerebral Venous Thrombosis -- 13. Parenchymatous Hemorrhage -- 14. Aneurysmal Subarachnoid Hemorrhage -- 15. Brain Vascular Malformations -- 16. Spinal Cord Ischemia -- 17. Overview of Laboratory Studies -- 18. Computed Tomography-Based Evaluation of Cerebrovascular Disease -- 19. Magnetic Resonance Imaging -- 20. Conventional Angiography -- 21. Ultrasonography -- 22. Single-Photon Emission Computed Tomography -- 23. Arterial Dissections -- 24. Collagen Vascular and Infectious Diseases -- 25. Moyamoya Disease -- 26. Fibromuscular Dysplasia -- 27. Migraine -- 28. Hypertensive Encephalopathy -- 29. Vascular Cognitive Impairment and Dementia -- 30. Atherosclerotic Disease of the Aortic Arch -- 31. Binswanger's Disease -- 32. CADASIL -- 33. Cerebral Amyloid Angiopathy -- 34. Coagulopathies -- 35. Stroke with Substance Abuse -- 36. Cardiac Diseases, Including Patent Foramen Ovale -- 37. Vascular Biology and Atherosclerosis -- 38. Thrombosis and Thrombolysis -- 39. Cerebral Blood Flow and Metabolism in Cerebrovascular Disease -- 40. Histopathology of Cerebral Ischemia -- 41. Excitotoxicity -- 42. Apoptosis -- 43. White Matter Injury -- 44. Inflammation -- 45. Intracellular Signaling: Mediators and Protective Responses.; 46. Recovery of Function.-A. Medical Therapy -- 47. Prehospital and Emergency Department Care of the Acute Stroke Patient -- 48. Intravenous Thrombolysis for Acute Stroke -- 49. Intra-arterial Thrombolysis for Acute Stroke -- 50. Antithrombotic Therapy for Acute Stroke -- 51. General Stroke Management and Stroke Units -- 52. Critical Care of the Acute Stroke Patient -- 53. Pharmacologic Modification of Acute Stroke (Neuroprotection) -- 54. Treatment of "Other" Stroke Etiologies -- 55. Medical Therapy of Intracerebral and Intraventricular Hemorrhage -- 56. Rehabilitation and Recovery of the Stroke Patient -- 57. Antiplatelet Therapy for Secondary Stroke Prevention -- 58. Medical Management of Intracranial and Extracranial Atherosclerosis -- 59. Stenting of Intracranial and Extracranial Arterial Stenoses -- 60. Secondary Prevention of Cardioembolic Stroke -- 61. Clinical Trials for Stroke B. Surgical Therapy -- 62. Inherited Vascular Diseases of Neurosurgical Significance -- 63. Intracranial Hemorrhage -- 64. Intraventricular Hemorrhage -- 65. Symptomatic Carotid Occlusive Disease -- 66. Asymptomatic Carotid Occlusive Disease -- 67. Intracranial Aneurysms -- 68. Arteriovenous Malformations -- 69. Cavernous and Venous Malformations -- 70. Dural Arteriovenous Malformations -- 71. Moyamoya Disease: Surgical Aspects -- 72. Spinal Vascular Malformations -- 73. Cerebral Vasospasm -- 74. Extracranial-Intracranial Bypass for Cerebral Ischemia -- 75. Cerebral Infarction: Surgical Treatment -- 76. Cerebellar Infarction and Hemorrhage -- 77. Nontraumatic Intracranial Arterial Dissection -- 78. Interventional Neuroradiologic Therapy -- 79. Standards for Surgical Care of Stroke, Circa 2000.