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This best-selling resource has a worldwide reputation as the leader in its field. Focusing on human immunology and biology, while also reporting on scientific experimentation and advancement, it provides comprehensive coverage of state-of-the-art basic science as well as authoritative guidance on the practical aspects of day-to-day diagnosis and management. This new edition includes 700 full-color illustrations and a new, more accessible format to make finding information a snap. And this Expert Consult Premium Edition not only offers online access to the complete contents of the 2-volume set, fully searchable, but also regular online updates, and much more. Includes a glossary of allergy and immunology for quick and easy reference. Contains keypoints and clinical pearls highlighted for ease of use. Incorporates downloadable patient education sheets, downloadable illustrations, and links to useful online resources both for you and for your patients. Offers contributions from hundreds of international authorities for world-class expertise in overcoming any clinical challenge. Contains 200 new illustrations, 700 in all, to better illustrate complex immunology. Covers the very latest in the field, including hot topics such as latex allergy and immunotherapy. Utilizes a new, more user-friendly full-color format for easier reference. Includes online access to the entire contents of the book, fully searchable, with links to MEDLINE abstracts for all of the references. Keeps you completely current through regular online updates, including entire chapters rewritten or added over time, to reflect the continuous new developments in the field.… (more)
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Volume 1
Section A: Immunology
The immune system, an overview / William T Sherer and Thomas A Fleisher
Molecular biology and genetic engineering / Sudhir Gupta and Leman Yel
Principles and application of genetics / Dirkje S. Postma
Genetics of allergic disease and asthma / Julian M. Hopkin and Taro Shirakawa
Immunoglobulin structure and function / James T. Li
The complement system / Jerry Winkelstein, et. al.
Synthesis and regulation of immunoglobin E. / Lisa Cameron and Donata Vercelli
Signal transduction / Donald W. MacGlashan
Cellular adhesion in inflammation / Bruce S. Bochner
Cytokines in allergic inflammation / Larry Borish and Lanny J. Rosenwasser
Chemokines in cell movement and inflammation / Rafeul Alam
Antigen presentation and immunoregulation / Martien L. Kapsenberg and Henk M. Jansen
Mast cell-derived mediators / Martin K. Church, et. al.
Lipid mediators of hypersensitivity and inflammation / Edward J. Goetzl
Neuronal control of airway function in allergy / Bradley J. Undem and Brendan J. Canning
Biochemical events in basophil or mast cell activation and mediator release / Reuben P. Siraganian
Biology of lymphocytes / Lauren Cohn and Anuradha Ray
Biology and role of neutrophils in asthma / Antonio Maurizio Vignola and jean Bousquet
Biology of eosinophils / Hirohito Kita, et. al.
Biology of mast cells / John J. Ryan and Thomas F. Huff
Biology of basophils / John T. Schroeder and Lawrence M. Lichtenstein
Biology of monocytes and macrophages / William J. Calhoun
Biology of epithelial cells / David Proud
Biology of endothelial cells / Hedwig S. Murphy, et. al.
Biology of airway smooth muscle cells / Reynold a. Panettieri, Jr. and Aili L. Lazaar
Apoptosis of inflammatory cells / Adriano Giorgio Rossi
Delayed-type hypersensitivity and cellular immunity: Effector/regulator molecules and mechanisms / Philip W. Askenase
Allergic inflammation: Initiation, progression, and resolution / Sultan Niazi, et. al.
Animal models of asthma / William R. Henderson, Jr. and Matthew J. Lodewick
Pathophysiology of allergic inflammation / Peter J. Burnes
Immunopathology of allergic airway inflammation / Pota Christodoulpoulos
Section B: Aerobiology and Diagnosis of Allergy
Air pollution: Indoor and outdoor / David B. Keden
Aerobiology of outdoor allergens / Robert E. Esch and Robert K. Bush
Indoor allergens / Thomas A.E. Platts-Mills
Preparation and standardization of allergen extracts / Richard F. Lockey, et. al.
Allergen structure and function / Geoffrey Alexander Stewart and Clive Robinson
Laboratory tests for allergic and immunodeficiency diseases / Robert G. Hamilton
In vivo methods for study of allergy: Skin tests, techniques, and interpretation / Pascal Demoly, et. al.
Nasal provocation testing / Karalasingam Rajakulasingam
Brachial challenge testing / James E. Fish and Stephen P. Peters
Section C: Physiology
Structural and functional cutaneous immunology / Douglas A. Plager, et. al.
Immunologic and nonimmunologic lung defense mechanisms / Kenneth S. Knox and Homer L. Twigg III
Airway smooth muscle and related extracellular matrix in normal and asthmatic lung / Scott S. Wagers, et. al.
Development, structure and physiology in normal and asthmatic lung / Scott S. Wagers, et. al.
Airway, mucus and the mucociliary system / John V. Fahy
Aerosols / Thomas G O'Riordan and Gerald C. Smaldone
Anatomy and physiology of the nose and control of nasal airflow / Ronald Eccles
Section D: Pharmacology
Principles of pharmacotherapeutics / H. William Kelly and Hengameh Heiderian Raissy
Beta-adrenergic agonists / Harold S. Nelson
Theophylline and phosphodiesterase inhibitors / Peter J. Barnes
Antihistamines / E. Estelle R. Simons
Basic science of glucocorticoids / Robert P Schleimer
Clinical science of glucocorticoids / Joseph D. Spahn, et. al.
The chromosomes: Cromolyn sodium and nedocromil sodium / Stephen T. Holgate and Alan M. Edwards
Cholinergic mechanisms and anticholinergic therapy in respiratory diseases / William M. L. Bowerfind, et. al.
Antileukotriene therapy / Sally E. Wenzel
Immunomodulators / Arthur Kavanaugh and David H. Broide
Volume 2
Section E: Clinical Science
Cell-mediated immunity in health and disease / Burton Zweiman
Immune complexes and allergic disease / Michael M. Frank and C. Garren Hester
Primary immunodeficiency diseases / Rebecca Hatcher Buckley
Approach to the patient with recurrent infections / Mark Ballow and Kathleen M. O'Neil
Human immunodeficiency virus and allergic disease / Mary E. Paul and William T. Shearer
Clinical significance of immunoglobulin E / Dennis R. Ownby
Eosinophilia and Eosinophil-related disorders / Peter F. Weller
Epidemiology of asthma and allergic diseases / Erika Avila Tang, et. al.
Natural history, development, and prevention of allergic disease in childhood / Erika von Mutius and Fernando D. Martinez
Asthma pathogenesis / William W. Busse, et. al.
Pathology of asthma compared with chronic obstructive pulmonary disease / Peter Jeffrey
Asthma in infancy and childhood / Mark H. Moss
Asthma in adults: Evaluation and management / Nizar N. Jarjour
Asthma guidelines and outcomes / Louis-Philippe Boulet
Asthma and allergic diseases during pregnancy / Michael Schatz, et. al.
Exercise-induced airway narrowing / E.R. McFadden, Jr.
Occupational asthma / Jean-Luc Malo and Moira Chan Yeung
Allergic bronchopulmonary aspergillosis / Paul A. Greenberger
Hypersensitivity pneumonitis / Jordan N. Fink, et. al.
Allergic and nonallergic rhinitis / Peter H. Howarth
Endoscopy of the upper airway / William K. Dolen and John C. Selner
Nasal polyps and sinusitis / Claus Bachart and Paul van Cauwenberge
Otitis media / David P. Skoner, et. al.
Immunotherapy for inhalant allergens / Harold S. Nelson
Insect allergy / David B.K. Golden
Natural rubber latex allergy / John W. Yunginger
Anaphylaxis and anaphylactoid reactions / Philip L. Lieberman
Mastocytosis syndromes / Dean D. Metcalfe
Urticaria and angioedema / Allen P. Kaplan
Atopic dermatitis / Mark Boguniewiez and Donald Y.M. Leung
Contact dermatitis / P. Regine Mydlarski, et. al.
Allergic and immunologic disorders of the eye / Neal P. Barney and Frank M. Graziano
Adverse reactions to foods / High A. Sampson
Adverse reactions to food and drug additives / Robert K. Bush, et. al.
Adverse reactions to vaccines / John M. Kelso
Drug allergy / N. Franklin Adkinson, Jr.
Sensitivity to aspirin and nonsteroidal anti-inflammatory drugs / Donald D. Stevenson, et. al.
Unconventional theories and unproved methods in allergy / Abba I. terr
Appendices:
Human Chemokines
Cluster of differentiation (CD) molecules