Paul's Fundamental Immunology

by M.F. Flajnik (Editor)

Other authorsSteven Holland (Editor), Nevil Singh (Editor)
Ebook, 2023

Status

Available

Call number

Online - See item details for access

Publication

Philadelphia : Wolters Kluwer, 8th edition

ISBN

9781975142513

Description

Selected as a Doody's Core Title for 2022! Defining the field of immunology for 40 years, Paul's Fundamental Immunology continues to provide detailed, authoritative, up-to-date information that uniquely bridges the gap between basic immunology and the disease process. The fully revised 8th edition maintains the excellence established by Dr. William E. Paul, who passed away in 2015, and is now under new editorial leadership of Drs. Martin F. Flajnik, Nevil J. Singh, and Steven M. Holland. It's an ideal reference and gold standard text for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role.  Reflects the latest advances in the field, including current insights on immune system function, both basic and translational.  Contains 50 chapters written by leaders in all subfields of immunology.  Provides extensive coverage of the molecular biology that explains the dynamics underlying immune disorders and their treatment.  Includes 10 entirely new chapters covering invertebrate and plant immunity, eosinophils, innate lymphoid cells, gamma/delta T cells, NKT and MAIT cells, immunometabolism, maternal-fetal immunology and more.  Contains abundant full-color illustrations and tables that provide essential information at a glance.  Features annual updates from the authors to the VST version, keeping you current with changes in this dynamic field from the experts.    Enrich Your eBook Reading Experience  Read directly on your preferred device(s), such as computer, tablet, or smartphone.  Easily convert to audiobook, powering your content with natural language text-to-speech. … (more)

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CONTENTS:
Overview of the immune system
History of immunology
The insect immune system
Evolution of the vertebrate and lower deuterostome immune system
The plant immune system
Immunometabolism
Regulated cell death in the immune system
Lymphoid tissues and organs
Type I cytokines, inteferons, and their receptors
Tumor necrosis factor superfamily of cytokines and receptors
Chemokines and chemokine receptors
Pattern recognition receptors and the IL
1 family
The complement system
Neutrophils
Macrophages
Mast cells and basophils
Eosinophils
The biology of natural killer cells and innate lymphoid cells
The major histocompatibility complex
Classical antigen processing and presentation
Immunogloblins: structure and function
Immunogobulins: molecular genetics
T cell antigen receptors and antigen recognition
Antigen receptor signaling
B cell development in mice
B cell responses
T cell development in the thymus
CD4 helper T cells: differentiation, flexibility, and heterogeneity
Regulatory T cells
CD8 T cell memory
Cytotoxic effector functions
Immunologic tolerance
Fc receptors and their role in immune regulation and inflammation
Dendritic cells
Gamma delta T cells
CD1-restricted T cells
Mucosal-associated invariant T cells and other MR1-reactive T cells
The mucosal immune system
Introduction to neuroimmunology
Vaccines
Maternal-fetal immunology
Response to parasites
Immune responses to bacteria
Response to viruses
Immunology of HIV infection
Autoimmunity and autoimmune diseases
Immunologic mechanisms of allergic disorders
Transplantation immunology
Cancer immunology and immunotherapy
Inborn errors of immunity.
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