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In this lecture, Dr. Karyn Purvis, Rees-Jones Director of the TCU Institute of Child Development, explores the neuroscience behind chemical imbalances that often are at play in the brains of children from hard places. While understanding specific neurotransmitters and their levels are not essential tools of Trust-Based Relational Intervention (TBRI), awareness of neuroscience and brain development can enhance the treatment of emotionally and behaviorally fragile children. Running time: 47 minutes.