The Big Bang Theory: Season 1 (of 12)

Physicists Leonard and Sheldon understand everything from the inescapable gravitational pull of a black hole to the intricate structure of the atom. But take those atoms and assemble them into a woman, and their comprehension comes to a grinding halt. And when Penny, a woman with all those atoms in all the right places, moves in across the hall, Leonard and Sheldon's universe begins to expand in ways they never could have imagined.